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ArchR: Processing scATAC sequencing data

ArchR is a R package used for the analysis of scATAC sequencing data. After processing raw scRNAseq FASTQ files using CellRanger.

Installation

Installation requires the packages: devtools, and Bioconductor packages.

  1. Install devtools

if (!requireNamespace("devtools", quietly = TRUE)) install.packages("devtools")
2. Install Bioconductor

if (!requireNamespace("BiocManager", quietly = TRUE)) install.packages("BiocManager")
  1. Install ArchR
    devtools::install_github("GreenleafLab/ArchR", ref="master", repos = BiocManager::repositories())
    

Alternatively, Seurat is a frequently used R package to analyze both scRNA and scATAC sequencing data.

References:

  • Article: https://www.nature.com/articles/s41588-021-00790-6
  • Github page: https://github.com/GreenleafLab/ArchR

Reference:

  • Axel Rosendahl Huber