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cBioPortal

Description

The cBioPortal for Cancer Genomics is an open-access, open-source resource for interactive exploration of multidimensional cancer genomics data sets including molecular profiles and clinical attributes from large-scale cancer genomics projects.

The portal supports and stores non-synonymous mutations, DNA copy-number data (putative, discrete values per gene, e.g. "deeply deleted" or "amplified", as well as log2 or linear copy number data), mRNA and microRNA expression data, protein-level and phosphoprotein level data (RPPA or mass spectrometry based), DNA methylation data, and de-identified clinical data. However, for many studies only somatic mutation data and limited clinical data are available. For TCGA studies, the other data types are also available. Germline mutations are supported by cBioPortal, but are, with a few exceptions, not available in the public instance.

Data access

Click here to visualize the list of all the available datasets in cBioPortal and download the data.

Citing in Publications and Presentations

When using data from cBioPortal, please cite the following portal papers:

  • Cerami et al. The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data. Cancer Discovery. May 2012 2; 401. PubMed.
  • Gao et al. Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal. Sci. Signal. 6, pl1 (2013). PubMed.

Remember to also cite the source of the data if you are using a publicly available dataset.

Click here to learn more about how to cite cBioPortal.

Reference

  • Paula Gomis
  • Monica Sanchez